Does Tirzepatide Work for Weight Loss?

It's a new day for weight loss for people who have been struggling with the chronic disease of obesity. While some well-known weight-loss drugs have been making headlines for their incredible results, there's a new drug poised to become the best-selling drug of all time. It's called tirzepatide. Unlike weight-loss medications that must be administered daily, tirzepatide is a peptide that's taken once weekly to help:

• Reduce appetite
• Improve insulin sensitivity
• Improve sugar metabolism

Also known under the label of Mounjaro, tirzepatide gained U.S. Food and Drug Administration (FDA) approval as a treatment for improving glycemic control in adults with type 2 diabetes. It is now on track to gain approval as a weight-loss drug. Currently, tirzepatide can be used on an off-label basis for treating obesity. The once-weekly subcutaneous injections for administering tirzepatide use incremental dose increases. Keep reading to learn more about using tirzepatid for weight loss.

Exciting Research Supporting Tirzepatide for Weight Loss

When used in conjunction with changes in diet and exercise, tirzepatide may help people to lose significant amounts of weight. The research behind tirzepatide's benefit for weight loss is encouraging. To test the drug's effectiveness for helping individuals to lose weight, researchers conducted a double-blind trial involving 2,539 adults with a body-mass index (BMI) of 30 or more. Participants with BMIs of 27 or more were allowed if they fit the criteria for having at least one weight-related complication. During the study, participants received either tirzepatide or placebo for 72 weeks. At the conclusion of the 72-week trial, researchers found that trial participants given 5 milligrams, 10 milligrams, or 15 milligrams of tirzepatide once weekly experienced substantial, sustained weight loss.

Just how impressive was the weight loss for patients given tirzepatide? The trial found that patients who received a high dose of the drug lost an astonishing 22.5% of their body weight on average. The average weight loss among the group was around 52 pounds. For those keeping count, this is far better than what any current weight-loss medication available today has ever been proven to do. In trials involving the competing drugs of Wegovy and Saxenda, patients saw reductions in body weight totaling just 5% to 15%.

What Makes Tirzepatide Different from Other Weight Loss Drugs?

Tirzepatide has a lot in common with the current popular weight-loss drugs on the market. Like existing weight-loss drugs, tirzepatide is administered by injection. Tirzepatide also works in a way that's similar to how other popular drugs trigger weight loss. Like these other drugs, tirzepatide belongs to a class of drugs called GLP-1 agonists that work by mimicking a natural hormone in the body that helps to drastically reduce appetite and food intake.

What sets tirzepatide apart is that this particular drug also mimics a second hormone called gastric inhibitory peptide (GIP). What makes GIP both significant and remarkable in the context of promoting weight loss isn't just that it has a powerful ability to reduce appetite. What may be an even bigger benefit is that the GIP found within tirzepatide actually improves the ways that the body breaks down fats and sugars.

When taken together once a week using a tirzepatide injection, GIP and GLP-1 are integrated to create complementary effects. In models, GIP has been proven to be powerful for decreasing food intake while also boosting energy expenditure. When combining GIP with GLP-1, much greater effects on markers of metabolic dysregulation have been observed. In simple terms, this means big changes in body weight, lipids, and glucose. The doubled-up benefits of tirzepatide are behind predictions that this weight-loss drug will become the best-selling drug of all time!

How Do I Get Tirzepatide?

Due to its approved off-label status as a treatment for obesity, tirzepatide is currently available to order online. TeleWellnessMD^® is a direct source for tirzepatide. Using a telehealth consultation, patients can access a two-month supply of this peptide therapy for weight loss. Tirzepatide can be taken with or without food. While shortages of weight-loss drugs over the past year have made getting started with this journey hard for many people, patients ordering through TeleWellnessMD^® can receive their orders directly without long waiting periods. Book your consultation to order tirzepatide online today!