IGF-1, or Insulin-like Growth Factor 1, is a naturally occurring protein produced primarily by the liver. It plays an important role in normal growth, development and cellular signaling throughout the body.
Because IGF-1 interacts with multiple tissues and organ systems, it has been the subject of extensive scientific research. Understanding its role can help provide insight into how the body regulates growth and maintenance throughout different stages of life.
This article is intended for educational purposes only and should not be considered medical advice, diagnosis or treatment.
Insulin-like Growth Factor 1 (IGF-1) is a protein that helps support normal growth and development. It is produced primarily by the liver in response to signals from growth hormone and participates in cellular communication throughout the body.
Despite its name, IGF-1 is not insulin. However, it shares some structural similarities and is involved in pathways related to growth, metabolism and tissue maintenance.
IGF-1 is present throughout life, with levels naturally changing based on age, genetics, nutrition, activity level and overall health status.
Production of IGF-1 is influenced by growth hormone, which is released by the pituitary gland. When growth hormone signals the liver, IGF-1 is produced and circulated throughout the body.
Researchers continue to study the complex relationship between growth hormone, IGF-1, nutrition, sleep and other physiological factors.
Many factors may contribute to natural variations in IGF-1 levels, including:
Because these factors vary from person to person, IGF-1 levels can differ significantly among individuals.
IGF-1 plays an important role during childhood and adolescence, when growth and development occur most rapidly. Levels generally increase during puberty and gradually change throughout adulthood as part of the body's normal physiological processes.
Researchers continue to explore how IGF-1 interacts with various tissues and signaling pathways across the lifespan.
Scientists continue to investigate the role of growth factors such as IGF-1 in human physiology. Areas of ongoing research include cellular signaling, growth regulation, tissue maintenance, and age-related biological changes.
As research evolves, our understanding of these complex pathways continues to expand.
Maintaining overall wellness involves many factors, including nutrition, physical activity, sleep, stress management, and regular medical care.
If you are interested in learning more about provider-guided wellness strategies, TeleWellnessMD® offers educational resources and consultations focused on individualized health and wellness goals.
Explore Wellness Support Options
This content is for educational and informational purposes only and should not be interpreted as medical advice. TeleWellnessMD® is a technology platform that connects patients with licensed healthcare providers. TeleWellnessMD® does not practice medicine, provide medical advice, or dispense medications. All therapies require evaluation and approval by a licensed healthcare provider. Results may vary.