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The Mental and Physical Health Benefits of NAD+

NAD+ is often referred to as the Fountain of Youth. Learn about its health benefits.



A depletion of nicotinamide adenine dinucleotide (also referred to as NAD+) within the body exacerbates many physical and mental health conditions. NAD+ is a metabolic co-enzyme pivotal in repairing damaged mitochondria within the cells. In addition to this role, NAD+ also plays a significant part in bolstering the immune system and enhancing cellular metabolism.

Unfortunately, a person's level of NAD+ becomes depleted as they age. This reduction in NAD levels can lead to advanced aging and adverse health outcomes. For example, chronic illnesses may develop when poor lifestyle and environmental factors combine with lower NAD+ levels. In addition, mitochondrial dysfunction may occur, leading to a variety of conditions, including Alzheimer's disease, anxiety, substance abuse, multiple sclerosis, and diabetes.

Restoring your NAD+ levels with supplementation can boost your body's ability to reduce inflammation, accelerate DNA repair, and increase energy. In addition to these physical benefits, you may experience significant relief from emotional stress and an enhancement in cognitive performance and mental health. If you're struggling with substance abuse, NAD+ may also help alleviate cravings. A study conducted in 2022 found that an increase in NAD+ was associated with a significant reduction in cravings, depression, and anxiety in those seeking treatment for substance abuse.

The Clinical Significance of NAD+ 

Over the last decade, significant research has taken place regarding the utility of NAD+ and healthy cellular metabolism. Studies show an accelerated decline of NAD+ levels within the cells of humans and rodents. While these levels can rise through dietary modification and an increase in physical activity, NAD+ levels will continue to decline as you age. The most effective method of modulating these levels is through pharmacological intervention.

Age-Related Disorders and NAD+ Supplementation

One of the most exciting areas of study regarding NAD+ supplementation is its positive effect on the lifespan of those with age-related degenerative disorders like Alzheimer's and Parkinson's. NAD+ plays an essential role in the cell's ability to adapt to stress, especially as you age. This decrease puts you at greater risk of developing a wide range of degenerative disorders. Emerging evidence from several studies suggests that increasing NAD+ levels may forestall the development of these diseases, increasing your lifespan and quality of life as you age.

This study further demonstrates that supplementation of NAD+ is still effective, even when administered at a relatively older age. Mice who received supplementation of NAD+ at two years of age saw a significant lifespan increase of over 5%. Not only did the specimens experience an increase in muscle strength and motor function, but they also showed considerable improvement in health at the mitochondrial level.

The implications of this study and others suggest that NAD+ supplementation could delay the onset of rare, rapid aging diseases. In addition, NAD+ could be helpful for a wide variety of neurodegenerative diseases. A review published in 2019 found that NAD+ plays an essential role in counteracting the development of Huntington's, Parkinson's, and Alzheimer's diseases. NAD+ can enhance neuronal resilience, facilitate healthy aging, and improve the quality of life for anyone interested in increasing their cognitive strength.

Who Can Benefit from NAD+?

NAD+ is particularly beneficial for those interested in counteracting cognitive decline as they get older. However, many other people can benefit from NAD+ supplementation. NAD+ may be right for you if you are interested in the following: 

  • Protecting your brain and increasing cellular resistance to stress
  • Enhancing and facilitating DNA repair
  • Regulating your circadian rhythm and improving your sleep quality
  • Increasing your energy levels
  • Maintaining an ideal weight

By including NAD+ supplementation in your lifestyle, you'll take a positive step in protecting your health as you age while enhancing your quality of life.

How to get a Prescription for NAD+

Schedule a consultation to speak with a medical provider about getting NAD+.



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