If you’ve been on a GLP-1 agonist like semaglutide or tirzepatide, you already know the benefits—reduced appetite, improved blood sugar control, and significant weight loss. But what happens when it’s time to taper off?
Many people face rebound weight gain, cravings, fatigue, and blood sugar instability as the medication wears off. That’s where MOTS-c—a mitochondrial peptide—can step in as a powerful tool to help bridge the gap and keep your results on track.
GLP-1s help manage glucose—but so does MOTS-c. This peptide activates AMPK, a metabolic master regulator that:
Perfect for maintaining glycemic control as your GLP-1 dose tapers down.
While GLP-1s suppress appetite to promote weight loss, MOTS-c enhances metabolic efficiency, helping your body naturally:
This allows your body to continue functioning like it’s in a calorie-efficient state—without relying on appetite suppression.
Many patients report energy crashes after coming off GLP-1s. MOTS-c combats this by:
It’s a true cellular-level reset that helps you feel strong and energized again.
One of the biggest fears of stopping GLP-1s is the dreaded rebound:
MOTS-c helps reduce that risk by supporting long-term metabolic health and helping you sustain new habits with greater resilience and energy.
When tapering off a powerful tool like a GLP-1, it’s crucial to have a smart, evidence-based transition strategy. At TeleWellnessMD, we:
• Monitor your labs and body composition
• Customize MOTS-c dosing protocols
• Offer ongoing support to help you stay accountable and feeling great
All peptides are prescribed by licensed providers and dispensed through FDA-approved compounding pharmacies—no gray market products here.
Ready to Transition Smarter?
GLP-1s helped you get started. Let MOTS-c help you stay the course.
Book your follow-up consultation with TeleWellnessMD and ask your provider if MOTS-c is the right next step in your wellness journey.